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Red ginseng
This product is the steamed dried root and rhizome of the cultivar of Panax ginseng C. A. Mey. of the Araliaceae family. It is harvested in autumn, washed, steamed, and dried.
The main root is spindle-shaped, cylindrical or flat square, 3 to 10 cm long and 1 to 2 cm in diameter. The surface is translucent, reddish brown, with occasional opaque dark yellow-brown patches, with longitudinal grooves, wrinkles and fine root marks; the upper part sometimes has intermittent inconspicuous ring marks; the lower part has 2 to 3 twisted and crossed lateral roots with curved fibrous roots or only fibrous root remnants. The rhizome (reed head) is 1 to 2 cm long, with several concave stem marks (reed bowls) on it, and some have 1 to 2 complete or broken adventitious roots (taro). The texture is hard and brittle, with a flat cross section and horny. The smell is slightly fragrant and unique, and the taste is sweet and slightly bitter.
(1) According to the test of [Identification] (1) under the ginseng item, except for the blurred outline of starch granules, other characteristics should be the same.
(2) According to the test of [Identification] (2) under the ginseng item, the same results should be shown.
The water content shall not exceed 120% (General Rule 0832 Method 2).
Other organochlorine pesticide residues shall be determined according to gas chromatography (General Rule 0521).
Chromatographic conditions and system suitability test Analytical column: capillary column (30mX0.32mmX0.25μm) with bonded cross-linked 14% propylphenyl dimethylsiloxane as the stationary liquid (DM1701 or the same type), verification column: capillary column (30mX0.32mmX0.25μm) with bonded cross-linked 5% phenylmethylsiloxane as the stationary liquid (DE5 or the same type); 63Ni-ECD electron capture detector; injection port temperature 230℃, detector temperature 300℃, non-split injection. Constant pressure control mode, initial flow rate is 1.5ml per minute. Program temperature rise: initial temperature 60℃, hold for 0.5 minutes, rise to 170℃ at 60℃ per minute, then rise to 220℃ at 15℃ per minute, hold for 5 minutes, then rise to 240℃ at 1℃ per minute, rise to 280℃ at 15℃ per minute, hold for 5 minutes. The number of theoretical plates calculated based on the pentachloronitrobenzene peak should not be less than 1X105, and the separation degree of two adjacent chromatographic peaks should be greater than 1.5. Preparation of mixed reference stock solution Accurately weigh appropriate amounts of pentachloronitrobenzene, hexachlorobenzene, heptachlor (heptachlor, heptachlor epoxide), chlordane (cis-chlordane, trans-chlordane, chlordane oxide) pesticide reference substances, accurately weigh, and dissolve them in n-hexane to prepare solutions containing about 100Mg per 1ml. Accurately measure 1 ml of each of the above-mentioned reference substance solutions, place them in the same 100 ml volumetric flask, add n-hexane to the mark, and shake well; or accurately measure 1 ml of the organochlorine pesticide mixed reference substance solution, place it in a 10 ml volumetric flask, add n-hexane to the mark, and shake well to obtain (each 1 ml contains 1 mg of each pesticide reference substance).
Preparation of mixed reference substance solution Accurately measure the above-mentioned mixed reference substance stock solution, and use n-hexane to prepare solutions containing 1 ng, 2 ng, 5 ng, 10 ng, 20 ng, 50 ng, and 100 ng per 1 ml. Preparation of test solution: Take the product, crush it into fine powder (pass through No. 2 sieve), take about 5g, accurately weigh, put it in a stoppered conical flask, add 30ml of water, shake for 10 minutes, accurately add 50ml of acetone, weigh the weight, ultrasonically treat (power 300W, frequency 40kHz) for 30 minutes, let cool, weigh the weight again, make up the lost weight with acetone, then add sodium chloride and accurately add 25ml of dichloromethane, weigh the weight, ultrasonically treat (power 300W, frequency 40kHz) for 15 minutes, let cool, weigh the weight again, make up the lost weight with dichloromethane, shake to fully dissolve the sodium chloride, let it stand, transfer it to a centrifuge tube, centrifuge (3000 revolutions per minute) for 3 minutes to completely separate the layers, transfer the upper organic phase to a stoppered conical flask containing an appropriate amount of anhydrous sodium sulfate, and let it stand for 30 minutes. Accurately measure 15mh and place it in a 40℃ water bath to decompress and concentrate to about 1ml, add about 5ml of n-hexane, decompress and concentrate to near dryness, dissolve it with n-hexane and transfer it to a 5ml volumetric flask, dilute to the scale, shake well, transfer it to a centrifuge tube, slowly add (9-10)lml of sulfuric acid solution, shake for 1 minute, centrifuge (3000 rpm) for 10 minutes, separate the supernatant, add 1ml of water, shake, and take the supernatant.
Determination method: Accurately aspirate 1/1 of the test solution and the mixed reference solution of the corresponding concentration, inject into the gas chromatograph, inject three times continuously, take the average value, and calculate according to the external standard method.
This product contains pentachloronitrobenzene not exceeding 0.1 mg/kg; heptachlor (the sum of heptachlor and heptachlor epoxide) not exceeding 0.05 mg/kg; chlordane (the sum of cis-chlordane, trans-chlordane and oxidized chlordane) not exceeding 0.1 mg/kg.
Determine according to high performance liquid chromatography (General Rule 0512).
Chromatographic conditions and system suitability test: Octadecylsilane bonded silica gel is used as filler; acetonitrile is used as mobile phase A and water is used as mobile phase B, and gradient elution is performed according to the provisions in the table below; the detection wavelength is 203 nmo, and the number of theoretical plates calculated based on the ginsenoside Rg peak should not be less than 6000.
Time (minutes) | Mobile phase A (%) | Mobile phase B (%) |
0~35
|
19
|
81
|
35 ~55
|
19→29
|
81→71 |
55 ~70
|
29
|
71 |
70~100
|
29→40
|
71→60 |
Raw Material Selection
Quality Inspection
Processing
Packaging
Quality Control
Storage and Transportation
Raw Material Selection
Chinese Herbal Medicine Cultivation: We strictly select Chinese herbal medicine cultivation bases from authentic medicinal material production areas to ensure the high quality of Chinese medicinal materials.
Herbal Medicine Procurement: We procure high-quality Chinese herbs from around the world to ensure that the herbs are pure, natural, and pollution-free.
Quality Inspection
Raw Material Testing: All purchased Chinese herbs must undergo strict quality inspection before entering the warehouse, including sensory indicators such as appearance, smell, and color, as well as physical and chemical indicators such as component analysis, heavy metal detection, and pesticide residue testing.
Processing
Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.
Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.
Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.
Selection
Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.
Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.
Packaging
Packaging Handling: In a clean packaging workshop, use modern packaging equipment to package the Chinese herbs, ensuring the sealing and hygiene of the packaging and extending the product's shelf life.
Label Identification: Each package is labeled with detailed information, including the name of the herb, specification, place of origin, production date, etc., ensuring the traceability of the product.
Quality Control
Process Monitoring: Strict quality monitoring is carried out at every stage of production to ensure that the products meet national standards and customer requirements.
Final Inspection: Every batch of products undergoes final quality inspection before leaving the factory, including appearance, composition, and microbial indicators, ensuring the safety and efficacy of the products.
Storage and Transportation
Storage: Store the products in warehouses that comply with GSP standards to ensure product quality and stability. Warehouse environment control includes temperature, humidity, and ventilation, ensuring that the herbs do not get damp or deteriorate.
Transportation: Use professional logistics transportation methods to ensure the safety and integrity of the products during transportation, delivering them to customers on time. We cooperate with multiple international logistics companies to ensure fast and efficient global delivery.
Raw Material Selection
Chinese Herbal Medicine Cultivation: We strictly select Chinese herbal medicine cultivation bases from authentic medicinal material production areas to ensure the high quality of Chinese medicinal materials.
Herbal Medicine Procurement: We procure high-quality Chinese herbs from around the world to ensure that the herbs are pure, natural, and pollution-free.
Quality Inspection
Raw Material Testing: All purchased Chinese herbs must undergo strict quality inspection before entering the warehouse, including sensory indicators such as appearance, smell, and color, as well as physical and chemical indicators such as component analysis, heavy metal detection, and pesticide residue testing.
Processing
Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.
Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.
Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.
Selection
Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.
Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.
Packaging
Packaging Handling: In a clean packaging workshop, use modern packaging equipment to package the Chinese herbs, ensuring the sealing and hygiene of the packaging and extending the product's shelf life.
Label Identification: Each package is labeled with detailed information, including the name of the herb, specification, place of origin, production date, etc., ensuring the traceability of the product.
Quality Control
Process Monitoring: Strict quality monitoring is carried out at every stage of production to ensure that the products meet national standards and customer requirements.
Final Inspection: Every batch of products undergoes final quality inspection before leaving the factory, including appearance, composition, and microbial indicators, ensuring the safety and efficacy of the products.
Storage and Transportation
Storage: Store the products in warehouses that comply with GSP standards to ensure product quality and stability. Warehouse environment control includes temperature, humidity, and ventilation, ensuring that the herbs do not get damp or deteriorate.
Transportation: Use professional logistics transportation methods to ensure the safety and integrity of the products during transportation, delivering them to customers on time. We cooperate with multiple international logistics companies to ensure fast and efficient global delivery.
Processing
Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.
Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.
Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.
Selection
Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.
Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.
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