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Alisma orientalis
This product is the dried tuber of Alisma orientate (Sam.) Juzep. or Alisma plantago-aquatica Linn. of the Alismataceae family. It is dug up in winter when the stems and leaves begin to wither, washed, dried, and the fibrous roots and rough bark are removed.
This product is spherical, elliptical or oval, 2 to 7 cm long and 2 to 6 cm in diameter. The surface is light yellow to light yellow-brown, with irregular transverse annular shallow grooves and many small protruding root marks, and some have tumor-like bud marks on the bottom. The texture is solid, the cross section is yellow-white, powdery, and has many pores. The smell is slight and the taste is slightly bitter.
(1) The powder of this product is light yellow-brown. There are many starch granules. Single granules are long oval, spherical or elliptical, with a diameter of 3 to 14 μm, and the umbilicus is herringbone, short slit or trident; compound granules are composed of 2 to 3 granules. The thin-walled cells are spherical, with many elliptical pits, which are integrated into pit groups. The pericytes of the endodermal cells are wavy, thick, lignified, and have sparse pore grooves. The oil chambers are mostly broken, and the intact ones are spherical with a diameter of 54 to 110 μm. Oil droplets can sometimes be seen in the secretory cells.
(2) Take 2g of the powder of this product, add 20ml of 70% ethanol, ultrasonically treat for 30 minutes, filter, evaporate the filtrate until there is no alcohol taste, pass it through a HP20 macroporous adsorption resin column (inner diameter 1cm, column height 5cm, 30% ethanol wet column), elute with 15ml of 30% ethanol, discard the eluent, elute with 15ml of 70% ethanol, collect the eluent, evaporate to dryness, add 1ml of methanol to dissolve the residue, and use it as the test solution. Take another 2g of the control medicinal material of Alisma orientalis and prepare the control medicinal material solution in the same way. Then take the 23-acetyl alisma alcohol B reference substance and the 23-acetyl alisma alcohol C reference substance, add methanol to prepare a solution containing 1mg per 1ml, and use it as the reference solution. According to the thin layer chromatography method (General Rule 0502), 10μ1 of each of the above four solutions was taken and spotted on the same silica gel GF254 thin layer plate, and developed with dichloromethane-methanol (15:1) as the developing solvent, developed, taken out, dried, sprayed with a mixed solution of 2% vanillin sulfuric acid solution-ethanol 1:9), heated at 105℃ until the spots were clearly colored, and inspected under sunlight and ultraviolet light (365nm). In the chromatogram of the test sample, spots of the same color or fluorescent spots appeared at the corresponding positions of the chromatogram of the reference medicinal material and the chromatogram of the reference substance.
The moisture content shall not exceed 14.0% (General Rule 0832 Method 2).
Total ash content shall not exceed 5.0% (General Rule 2302).
According to the hot leaching method under the determination method of alcohol-soluble extract (General Rule 2201), ethanol is used as the solvent, and the content shall not be less than 10.0%.
Determine according to high performance liquid chromatography (General Rule 0512). Chromatographic conditions and system suitability test Use octadecylsilane bonded silica gel as filler; acetonitrile as mobile phase A, water as mobile phase E, and perform gradient elution according to the provisions in the table below. The detection wavelength of 23-acetyl alismatol B is 208nm, and the detection wavelength of 23-acetyl alismatol C is 246nm. The number of theoretical plates calculated based on the 23-acetyl alismatol B peak should not be less than 3000.
Time (minutes) | Mobile phase A (%) | Mobile phase B (%) |
0~5 | 45 | 55 |
5~30 | 45→84 | 55→16 |
30~40 | 84 | 16 |
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Raw Material Selection
Chinese Herbal Medicine Cultivation: We strictly select Chinese herbal medicine cultivation bases from authentic medicinal material production areas to ensure the high quality of Chinese medicinal materials.
Herbal Medicine Procurement: We procure high-quality Chinese herbs from around the world to ensure that the herbs are pure, natural, and pollution-free.
Quality Inspection
Raw Material Testing: All purchased Chinese herbs must undergo strict quality inspection before entering the warehouse, including sensory indicators such as appearance, smell, and color, as well as physical and chemical indicators such as component analysis, heavy metal detection, and pesticide residue testing.
Processing
Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.
Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.
Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.
Selection
Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.
Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.
Packaging
Packaging Handling: In a clean packaging workshop, use modern packaging equipment to package the Chinese herbs, ensuring the sealing and hygiene of the packaging and extending the product's shelf life.
Label Identification: Each package is labeled with detailed information, including the name of the herb, specification, place of origin, production date, etc., ensuring the traceability of the product.
Quality Control
Process Monitoring: Strict quality monitoring is carried out at every stage of production to ensure that the products meet national standards and customer requirements.
Final Inspection: Every batch of products undergoes final quality inspection before leaving the factory, including appearance, composition, and microbial indicators, ensuring the safety and efficacy of the products.
Storage and Transportation
Storage: Store the products in warehouses that comply with GSP standards to ensure product quality and stability. Warehouse environment control includes temperature, humidity, and ventilation, ensuring that the herbs do not get damp or deteriorate.
Transportation: Use professional logistics transportation methods to ensure the safety and integrity of the products during transportation, delivering them to customers on time. We cooperate with multiple international logistics companies to ensure fast and efficient global delivery.
Raw Material Selection
Chinese Herbal Medicine Cultivation: We strictly select Chinese herbal medicine cultivation bases from authentic medicinal material production areas to ensure the high quality of Chinese medicinal materials.
Herbal Medicine Procurement: We procure high-quality Chinese herbs from around the world to ensure that the herbs are pure, natural, and pollution-free.
Quality Inspection
Raw Material Testing: All purchased Chinese herbs must undergo strict quality inspection before entering the warehouse, including sensory indicators such as appearance, smell, and color, as well as physical and chemical indicators such as component analysis, heavy metal detection, and pesticide residue testing.
Processing
Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.
Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.
Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.
Selection
Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.
Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.
Packaging
Packaging Handling: In a clean packaging workshop, use modern packaging equipment to package the Chinese herbs, ensuring the sealing and hygiene of the packaging and extending the product's shelf life.
Label Identification: Each package is labeled with detailed information, including the name of the herb, specification, place of origin, production date, etc., ensuring the traceability of the product.
Quality Control
Process Monitoring: Strict quality monitoring is carried out at every stage of production to ensure that the products meet national standards and customer requirements.
Final Inspection: Every batch of products undergoes final quality inspection before leaving the factory, including appearance, composition, and microbial indicators, ensuring the safety and efficacy of the products.
Storage and Transportation
Storage: Store the products in warehouses that comply with GSP standards to ensure product quality and stability. Warehouse environment control includes temperature, humidity, and ventilation, ensuring that the herbs do not get damp or deteriorate.
Transportation: Use professional logistics transportation methods to ensure the safety and integrity of the products during transportation, delivering them to customers on time. We cooperate with multiple international logistics companies to ensure fast and efficient global delivery.
Processing
Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.
Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.
Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.
Selection
Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.
Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.
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