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Licorice

This product is the dried root and rhizome of Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. of the Leguminosae family. It is dug up in spring and autumn, the fibrous roots are removed, and the product is dried in the sun.

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  • 【Character】

Licorice root is cylindrical, 25 to 100cm long and 0. 6 to 3. 5cm in diameter. The outer skin varies in tightness. The surface is reddish brown or gray brown, with obvious longitudinal wrinkles, grooves, lenticels and sparse fine root marks. The texture is solid, the cross-section is slightly fibrous, yellow-white, powdery, with obvious cambium rings, radial rays, and some cracks. The rhizome is cylindrical, with bud marks on the surface and pith in the middle of the cross section. Smell, taste
Sweet and special. The roots and rhizomes of Licorice are thick and woody, some are branched, and the outer skin is rough, mostly gray-brown or grey-brown. It is hard in texture, has more wood fibers and is less powdery. rhizome adventitious buds
Many and thick. The roots and rhizomes of Glycyrrhiza glabra are relatively solid in texture, with some branches, the outer skin is not rough, mostly grey-brown, and the lenticels are thin and not obvious.

  • 【Identification】

(1) Cross section of this product: The cork layer is composed of several rows of brown cells. The inner layer of the plug is narrow. The phloem has broad rays, many bends, and often cracks; the fibers are mostly bundled, non-lignified or slightly lignified, and the surrounding parenchyma cells often contain calcium oxalate square crystals; the sieve tube group is often deformed due to compression. The cambium within the bundle is obvious. The xylem rays are 3 to 5 rows of cells wide; there are many vessels with a diameter of about 160 μm; the wood fibers are in bundles, and the surrounding parenchyma cells also contain calcium oxalate square crystals. There is no pith in the center of the root; there is pith in the center of the rhizome. The powder is light brown. The fibers are in bundles, with a diameter of 8 to 14 μm, thick walls, and slight lignification. The surrounding parenchyma cells contain calcium oxalate square crystals to form crystal fibers. Calcium oxalate cubic crystals are common. Marginal pit ducts are larger and reticulated ducts are rare. Cork cells are reddish brown, polygonal, slightly woody.
(2) Take 1g of powder of this product, add 40ml of acetate, heat and reflux for 1 hour, filter, discard the brewing liquid, add 30ml of methanol to the residue, heat and reflux for 1 hour, filter, evaporate the filtrate to dryness, add 40ml of water to the residue to dissolve , extracted with n-butanol three times, 20ml each time, combined the n-butanol liquid, washed three times with water, discarded the water, evaporated the n-butanol liquid to dryness, added 5ml of methanol to the residue to dissolve, and used it as the test solution. Take another 1g of licorice control medicinal material and prepare the reference medicinal material solution in the same way. Then take the glycyrrhizic acid monosaddle salt reference substance, add methanol to make a solution containing 2mg per 1ml, and use it as the reference substance solution. According to the thin layer chromatography (General Chapter 0502) test, absorb 1 to 20 of each of the above three solutions, respectively point on the same silica gel G thin layer plate prepared with 1% sodium hydroxide solution, and use ethyl acetate-formic acid-glacial acetic acid. - Use water (15: 1: 1: 2) as a developing agent, unfold, take out, dry, spray with 10% sulfuric acid ethanol solution, heat at 105°C until the spots become clear, and inspect under ultraviolet light (365nm). In the chromatogram of the test product: the same color of fluorescent spots appears at the position corresponding to the chromatogram of the reference medicinal material; the same orange-yellow fluorescent spot appears at the position corresponding to the chromatogram of the reference substance.

  • 【examine】

The moisture content must not exceed 120% (General Rule 0832 Second Method).
The total ash content must not exceed 7.0% (General Chapter 2302).
Acid-insoluble ash shall not exceed 20% (General Chapter 2302).
Heavy metals and harmful elements are measured according to the determination method of lead, cadmium, arsenic, mercury, and copper (General Chapter 2321 Atomic Absorption Spectrophotometry or Inductively Coupled Plasma Mass Spectrometry). Lead must not exceed 5 mg/kg; cadmium must not exceed 1 mg/kg; arsenic must not exceed 1 mg/kg. More than 2 mg/kg; mercury must not exceed 0 2 mg/kg; copper must not exceed 20 mg/kg. Other organochlorine pesticide residues are determined according to the pesticide residue determination method (General Chapter 2341 Determination of Organochlorine Pesticide Residues - First Method). The content of pentachloronitrobenzene shall not exceed 0. lmg/kg.

  • 【Content determination】

Determine according to high performance liquid chromatography (General Chapter 0512).
Chromatographic conditions and system suitability test use octadecylsilane bonded silica gel as filler; use acetonitrile as mobile phase A, use 0.05% phosphoric acid solution as mobile phase B, and perform gradient elution as specified in the table below; detect wavelength The number of theoretical plates for 237nmo should not be less than 5,000 based on licorice peak.

Time (minutes) Mobile phase A (%) Mobile phase B (%)
0~8 19 81
8~35 19→50 81→50
35~36 50→100 50→0
36~40 100→19 0→81
Preparation of reference solution Take appropriate amount of glycyrrhizic acid reference and glycyrrhizic acid methyl ester reference, weigh them accurately, add 70% ethanol to make solutions containing 20 mg of glycyrrhizic acid and 0.2 mg of glycyrrhizic acid methyl ester per 1 ml, and obtain (weight of glycyrrhizic acid = weight of glycyrrhizic acid methyl ester / 1.0207). Preparation of test solution Take about 0.2 g of this product powder (passed through No. 3 sieve), weigh it accurately, put it in a stoppered conical bottle, accurately add 100 ml of 70% ethanol, plug it tightly, weigh it, ultrasonically treat it (power 250W, frequency 40kHz) for 30 minutes, let it cool, weigh it again, make up the lost weight with 70% ethanol, shake it well, filter it, and take the filtrate to obtain it.
Determination method Accurately aspirate 10 ml of reference solution and test solution respectively, inject them into liquid chromatograph, and determine them to obtain it.
Calculated on the basis of dry product, this product contains not less than 0.50% licorice (C21 H22 O16) and not less than 2.0% glycyrrhizic acid (C42H62O16).
Decoction pieces
  • 【Processing】
Licorice slices Remove impurities, wash, moisten, cut into thick slices, and dry.
  • 【Properties】
This product is in the form of thick slices of quasi-circular or oval shape. The outer skin is reddish brown or grayish brown with longitudinal wrinkles. The cut surface is slightly fibrous, the center is yellowish white, with obvious radiating texture and cambium ring. The texture is solid and powdery. The smell is slight, and the taste is sweet and special.
  • 【Inspection】
Total ash Same as medicinal materials, not more than 50%.
  • 【Content determination】
Same as medicinal materials, containing not less than 0.45% liquiritin (C21 H22 O9), and not less than 1.8% glycyrrhizic acid (C42H62O16).
  • 【Identification】 (Except cross section) 【Inspection】 (Water, heavy metals and harmful elements)
Same as medicinal materials.
  • 【Nature and flavor and meridians】
Sweet, flat. Enter the heart, lung, spleen, and stomach meridians.
  • 【Functions and indications】
Tonify the spleen and replenish qi, clear away heat and detoxify, eliminate phlegm and relieve cough, relieve pain, and harmonize various medicines. Used for spleen and stomach weakness, fatigue, palpitations and shortness of breath, cough and sputum, abdominal and limb cramps and pain, carbuncle, sore, and relieve drug toxicity and potency.
  • 【Usage and dosage】
2~10g.
  • 【Note】
It is not suitable to be used with seaweed, Beijing euphorbia, red euphorbia, gansui, and genkwa.
  • 【Storage】
Place in a ventilated and dry place to prevent moth.
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Production Process

Raw Material Selection

Quality Inspection

Processing

Packaging

Quality Control

Storage and Transportation

Raw Material Selection

Chinese Herbal Medicine Cultivation: We strictly select Chinese herbal medicine cultivation bases from authentic medicinal material production areas to ensure the high quality of Chinese medicinal materials.

Herbal Medicine Procurement: We procure high-quality Chinese herbs from around the world to ensure that the herbs are pure, natural, and pollution-free.

Quality Inspection

Raw Material Testing: All purchased Chinese herbs must undergo strict quality inspection before entering the warehouse, including sensory indicators such as appearance, smell, and color, as well as physical and chemical indicators such as component analysis, heavy metal detection, and pesticide residue testing.

Processing

Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.

Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.

Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.

Selection

Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.

Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.

Packaging

Packaging Handling: In a clean packaging workshop, use modern packaging equipment to package the Chinese herbs, ensuring the sealing and hygiene of the packaging and extending the product's shelf life.

Label Identification: Each package is labeled with detailed information, including the name of the herb, specification, place of origin, production date, etc., ensuring the traceability of the product.

Quality Control

Process Monitoring: Strict quality monitoring is carried out at every stage of production to ensure that the products meet national standards and customer requirements.

Final Inspection: Every batch of products undergoes final quality inspection before leaving the factory, including appearance, composition, and microbial indicators, ensuring the safety and efficacy of the products.

Storage and Transportation

Storage: Store the products in warehouses that comply with GSP standards to ensure product quality and stability. Warehouse environment control includes temperature, humidity, and ventilation, ensuring that the herbs do not get damp or deteriorate.

Transportation: Use professional logistics transportation methods to ensure the safety and integrity of the products during transportation, delivering them to customers on time. We cooperate with multiple international logistics companies to ensure fast and efficient global delivery.

Raw Material Selection

Chinese Herbal Medicine Cultivation: We strictly select Chinese herbal medicine cultivation bases from authentic medicinal material production areas to ensure the high quality of Chinese medicinal materials.

Herbal Medicine Procurement: We procure high-quality Chinese herbs from around the world to ensure that the herbs are pure, natural, and pollution-free.

Quality Inspection

Raw Material Testing: All purchased Chinese herbs must undergo strict quality inspection before entering the warehouse, including sensory indicators such as appearance, smell, and color, as well as physical and chemical indicators such as component analysis, heavy metal detection, and pesticide residue testing.

Processing

Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.

Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.

Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.

Selection

Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.

Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.

Packaging

Packaging Handling: In a clean packaging workshop, use modern packaging equipment to package the Chinese herbs, ensuring the sealing and hygiene of the packaging and extending the product's shelf life.

Label Identification: Each package is labeled with detailed information, including the name of the herb, specification, place of origin, production date, etc., ensuring the traceability of the product.

Quality Control

Process Monitoring: Strict quality monitoring is carried out at every stage of production to ensure that the products meet national standards and customer requirements.

Final Inspection: Every batch of products undergoes final quality inspection before leaving the factory, including appearance, composition, and microbial indicators, ensuring the safety and efficacy of the products.

Storage and Transportation

Storage: Store the products in warehouses that comply with GSP standards to ensure product quality and stability. Warehouse environment control includes temperature, humidity, and ventilation, ensuring that the herbs do not get damp or deteriorate.

Transportation: Use professional logistics transportation methods to ensure the safety and integrity of the products during transportation, delivering them to customers on time. We cooperate with multiple international logistics companies to ensure fast and efficient global delivery.

Processing

Cleaning: Thoroughly clean the Chinese herbs using clean water sources to remove dirt, impurities, and microorganisms.

Cutting: Based on the characteristics of different Chinese herbs, we adopt appropriate cutting processes, including slicing, segmenting, and shredding, to ensure the efficacy of the herbs and ease of use.

Drying: Use traditional sun-drying and modern drying techniques to ensure that the moisture content of Chinese herbs meets national standards, maintaining the efficacy and storage life of the herbs.

Selection

Screening: Carefully select the Chinese herbs to remove impurities, fragments, and non-conforming items, ensuring the purity and high quality of the herbs.

Sorting: Sort the herbs according to their specifications and grades to ensure product consistency and standardization.

After-Sales Service

Quality Assurance

All Chinese herbal products come with a one-year quality guarantee. If any quality issues are found within the warranty period, the company will provide replacement or refund services free of charge.

Quality Assurance

Product Warranty:All Chinese herbal products come with a one-year quality guarantee. If any quality issues are found within the warranty period, the company will provide replacement or refund services free of charge.

Quality Complaint Handling:Customers can submit quality complaints via phone, email, or online customer service, and the company will respond and resolve the issue within 24 hours.

Customer Consultation Service

The company offers 24-hour round-the-clock customer support. Customers can consult about product-related issues at any time via phone, email, or online customer service.

Customer Consultation Service

24/7 Customer Support:The company offers 24-hour round-the-clock customer support. Customers can consult about product-related issues at any time via phone, email, or online customer service.

Professional Consultation:The company has a team of professional Chinese medicine pharmacists who provide expert consultation on the use, health benefits, and efficacy of Chinese medicines.

Logistics Tracking Service

After placing an order, customers can check the order status through the company's website or customer service system to monitor logistics information in real-time.

Logistics Tracking Service

Order Tracking:After placing an order, customers can check the order status through the company's website or customer service system to monitor logistics information in real-time.

Delay Notifications:If there are any delays during the logistics process, the company will notify customers immediately and provide solutions.

User Training and Guidance

Each product comes with a detailed user manual to guide customers in the proper use of Chinese medicines.

User Training and Guidance

User Manuals:Each product comes with a detailed user manual to guide customers in the proper use of Chinese medicines.

Online Training:The company regularly holds online training courses to explain the usage methods, contraindications, and health benefits of Chinese medicines, helping customers use the products better.

Customer Feedback and Improvement

The company regularly sends satisfaction surveys to customers to collect their opinions and suggestions.

Customer Feedback and Improvement

Satisfaction Surveys:The company regularly sends satisfaction surveys to customers to collect their opinions and suggestions.

Continuous Improvement:Based on customer feedback, the company continuously improves its products and services to ensure customer satisfaction.

Global Customer Service

The company provides multilingual customer service to ensure smooth communication with overseas customers.

Global Customer Service

Multilingual Support:The company provides multilingual customer service to ensure smooth communication with overseas customers.

Localized Service:Setting up local service centers in major markets to provide faster after-sales support and service response.

Workshop Display

【 Sun Drying 】

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【 Processing Center 】

【 Testing Center 】